Congratulations to Sam Harris on what may be his first professional publication as a neuroscientist, Functional neuroimaging of belief, disbelief, and uncertainty, in Annals of Neurology. The link requires authenticate, and may only work if you access it from, say, inside a university library.
(UPDATE: A reader has provided a link to a page on Sam Harris’ Web site where you can click on the pdf link, and it does not require authentication.)
Here are the results of Harris, the first author, and his co-authors, which touch on the part of the brain I’m most interested in, the anterior cingulate cortex, which is responsible for error detection and the unpleasantness of pain.
The states of belief, disbelief, and uncertainty differentially activated distinct regions of the prefrontal and parietal cortices, as well as the basal ganglia.
Belief and disbelief differ from uncertainty in that both provide information that can subsequently inform behavior and emotion. The mechanism underlying this difference appears to involve the anterior cingulate cortex and the caudate. Although many areas of higher cognition are likely involved in assessing the truth-value of linguistic propositions, the final acceptance of a statement as true or its rejection as false appears to rely on more primitive, hedonic processing in the medial prefrontal cortex and the anterior insula. Truth may be beauty, and beauty truth, in more than a metaphorical sense, and false propositions may actually disgust us.
These results seem consistent, and no doubt extend, the findings of Antonio Damasio on how emotions constrain decision-making.
Update: Time Magazine has a good take of Harris’ results.